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Journal articles

Publications
- Journal articles
- Book chapters

2020

- Lee, L. P., Tan, K. Y., & Tan, C. H. (2020). Toxicity and cross-neutralization of snake venoms from two lesser-known arboreal pit vipers in Southeast Asia: Trimeresurus wiroti and Trimeresurus puniceus. Toxicon 185, 91-96.
- Liew, J. L., Tan, N. H., & Tan, C. H. (2020). Proteomics and preclinical antivenom neutralization of the mangrove pit viper (Trimeresurus purpureomaculatus, Malaysia) and white-lipped pit viper (Trimeresurus albolabris, Thailand) venoms. Acta Tropica 209, 105528-105528.
- Ratanabanangkoon, K., Tan, K. Y., Pruksaphon, K., Klinpayom, C., Gutiérrez, J. M., Quraishi, N. H., & Tan, C. H. (2020). A pan-specific antiserum produced by a novel immunization strategy shows a high spectrum of neutralization against neurotoxic snake venoms. Scientific Reports, 10(1), 1-12.
- Hia, Y. L., Tan, K. Y., & Tan, C. H. (2020). Comparative venom proteomics of banded krait (Bungarus fasciatus) from five geographical locales: Correlation of venom lethality, immunoreactivity and antivenom neutralization. Acta Tropica, 105460.
- Tan, K. Y., Wong, K. Y., Tan, N. H., & Tan, C. H. (2020). Quantitative proteomics of Naja annulifera (sub-Saharan snouted cobra) venom and neutralization activities of two antivenoms in Africa. International Journal of Biological Macromolecules 158, 605-616.
- Tan, K. Y., Ng, T. S., Bourges, A., Ismail, A. K., Maharani, T., Khomvilai, S., Sitprija, V., Tan, N. H. & Tan, C. H. (2020). Geographical variations in king cobra (Ophiophagus hannah) venom from Thailand, Malaysia, Indonesia and China: On venom lethality, antivenom immunoreactivity and in vivo neutralization. Acta tropica, 203, 105311.
- Tan, C. H., Liew, J. L., Navanesan, S., Sim, K. S., Tan, N. H., & Tan, K. Y. (2020). Cytotoxic and anticancer properties of the Malaysian mangrove pit viper (Trimeresurus purpureomaculatus) venom and its disintegrin (purpureomaculin). Journal of Venomous Animals and Toxins including Tropical Diseases, 26.
- Lingam, T. M. C., Tan, K. Y., & Tan, C. H. (2020). Proteomics and antivenom immunoprofiling of Russell’s viper (Daboia siamensis) venoms from Thailand and Indonesia. Journal of Venomous Animals and Toxins including Tropical Diseases, 26.

2019

Oh, A. M. F., Tan, C. H., Tan, K. Y., Quraishi, N. A., & Tan, N. H. (2019). Venom proteome of Bungarus sindanus (Sind krait) from Pakistan and in vivo cross-neutralization of toxicity using an Indian polyvalent antivenom. Journal of proteomics. 193, 243-254.
Tan, K. Y., Liew, J. L., Tan, N. H., Quah, E. S., Ismail, A. K., & Tan, C. H. (2019). Unlocking the secrets of banded coral snake (Calliophis intestinalis, Malaysia): A venom with proteome novelty, low toxicity and distinct antigenicity. Journal of proteomics. 192, 246-257.
Tan, C., Tan, K., Ng, T., Sim, S., & Tan, N. (2019). Venom Proteome of Spine-Bellied Sea Snake (Hydrophis curtus) from Penang, Malaysia: Toxicity Correlation, Immunoprofiling and Cross-Neutralization by Sea Snake Antivenom. Toxins, 11(1), 3.
Chong, H. P., Tan, K. Y., Tan, N. H., & Tan, C. H. (2019). Exploring the diversity and novelty of toxin genes in Naja sumatrana, the Equatorial spitting cobra from Malaysia through de novo venom-gland transcriptomics. Toxins, 11(2), 104.
Tan, C. H., Tan, K. Y., Ng, T. S., Quah, E. S., Ismail, A. K., Khomvilai, S., Sitprija, V., & Tan, N. H. (2019). Venomics of Trimeresurus (Popeia) nebularis, the Cameron Highlands Pit Viper from Malaysia: Insights into Venom Proteome, Toxicity and Neutralization of Antivenom. Toxins, 11(2), 95.
Tan, C. H., Wong, K. Y., Tan, N. H., Ng, T. S., & Tan, K. Y. (2019). Distinctive distribution of secretory phospholipases A2 in the venoms of Afro-Asian cobras (Subgenus: Naja, Afronaja, Boulengerina and Uraeus). Toxins, 11(2), 116.
Tan, K. Y., Liew, S. T., Tan, Q. Y., Abdul-Rahman, F. N., Azmi, N. I., Sim, S. M., ... & Tan, C. H. (2019). Evaluating the physicochemical properties and efficacy of recently expired and aged antivenom products from Thailand and Taiwan. Toxicon, 160, 55-58.
Tan, C. H., Wong, K. Y., Chong, H. P., Tan, N. H., & Tan, K. Y. (2019). Proteomic insights into short neurotoxin-driven, highly neurotoxic venom of Philippine cobra (Naja philippinensis) and toxicity correlation of cobra envenomation in Asia. Journal of proteomics, 103418.
Lingam, T. M. C., Tan, K. Y., & Tan, C. H. (2019). Thai Russell's viper monospecific antivenom is immunoreactive and effective in neutralizing the venom of Daboia siamensis from java, Indonesia. Toxicon.

2018

Ratanabanangkoon, K., Simsiriwong, P., Pruksaphon, K., Tan, K. Y., Chantrathonkul, B., Eursakun, S., & Tan, C. H. (2018). An in vitro potency assay using nicotinic acetylcholine receptor binding works well with antivenoms against Bungarus candidus and Naja naja. Scientific reports, 8(1), 9716.
Faisal, T., Tan, K. Y., Sim, S. M., Quraishi, N., Tan, N. H., & Tan, C. H. (2018). Proteomics, functional characterization and antivenom neutralization of the venom of Pakistani Russell's viper (Daboia russelii) from the wild. Journal of proteomics 138:1-13.
Tan, K. Y., Tan, N. H., & Tan, C. H. (2018). Venom proteomics and antivenom neutralization for the Chinese eastern Russell’s viper, Daboia siamensis from Guangxi and Taiwan. Scientific reports, 8(1), 8545.
Wong, K. Y., Tan, C. H., Tan, K. Y., Quraishi, N. H., & Tan, N. H. (2018). Elucidating the biogeographical variation of the venom of Naja naja (spectacled cobra) from Pakistan through a venom-decomplexing proteomic study. Journal of proteomics, 175, 156-173.

2017

Tan, N. H., Wong, K. Y., & Tan, C. H. (2017). Venomics of Naja sputatrix, the Javan spitting cobra: A short neurotoxin-driven venom needing improved antivenom neutralization. Journal of Proteomics, 157, 18-32.
Tan, C. H., Tan, K. Y., Yap, M. K. K., & Tan, N. H. (2017). Venomics of Tropidolaemus wagleri, the sexually dimorphic temple pit viper: Unveiling a deeply conserved atypical toxin arsenal. Scientific Reports, 7.
Tan, K. Y., Tan, C. H., Chanhome, L., & Tan, N. H. (2017). Comparative venom gland transcriptomics of Naja kaouthia (monocled cobra) from Malaysia and Thailand: elucidating geographical venom variation and insights into sequence novelty. PeerJ, 5, e3142.
Tan, C. H., Liew, J. L., Tan, N. H., Ismail, A. K., Maharani, T., Khomvilai, S., & Sitprija, V. (2017). Cross reactivity and lethality neutralization of venoms of Indonesian Trimeresurus complex species by Thai Green Pit Viper Antivenom. Toxicon, 140, 32-37.
Ratanabanangkoon, K., Simsiriwong, P., Pruksaphon, K., Tan, K. Y., Eursakun, S., Tan, C. H., ... & Tan, N. H. (2017). A novel in vitro potency assay of antisera against Thai Naja kaouthia based on nicotinic acetylcholine receptor binding. Scientific reports, 7(1), 8545.
Tan, C. H., Wong, K. Y., Tan, K. Y., & Tan, N. H. (2017). Venom proteome of the yellow-lipped sea krait, Laticauda colubrina from Bali: Insights into subvenomic diversity, venom antigenicity and cross-neutralization by antivenom. Journal of proteomics, 166, 48-58.
Oh, A. M. F., Tan, C. H., Ariaranee, G. C., Quraishi, N., & Tan, N. H. (2017). Venomics of Bungarus caeruleus (Indian krait): Comparable venom profiles, variable immunoreactivities among specimens from Sri Lanka, India and Pakistan. Journal of Proteomics.

2016

Tan, C. H., Tan, K. Y., & Tan, N. H. (2016). Revisiting Notechis scutatus venom: on shotgun proteomics and neutralization by the “bivalent” Sea Snake Antivenom. Journal of proteomics, 144, 33-38.
Ratanabanangkoon, K., Tan, K. Y., Eursakun, S., Tan, C. H., Simsiriwong, P., Pamornsakda, T., ... & Tan, N. H. (2016). A simple and novel strategy for the production of a Pan-specific antiserum against elapid snakes of Asia. PLoS Negl Trop Dis, 10(4), e0004565.
Tan, K. Y., Tan, C. H., Fung, S. Y., & Tan, N. H. (2016). Neutralization of the Principal Toxins from the Venoms of Thai Naja kaouthia and Malaysian Hydrophis schistosus: Insights into Toxin-Specific Neutralization by Two Different Antivenoms. Toxins, 8(4), 86.
Tan, K. Y., Tan, C. H., Sim, S. M., Fung, S. Y., & Tan, N. H. (2016). Geographical venom variations of the Southeast Asian monocled cobra (Naja kaouthia): venom-induced neuromuscular depression and antivenom neutralization. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 185, 77-86.
Tan, C. H., Fung, S. Y., Yap, M. K. K., Leong, P. K., Liew, J. L., & Tan, N. H. (2016). Unveiling the elusive and exotic: Venomics of the Malayan blue coral snake (Calliophis bivirgata flaviceps). Journal of proteomics, 132, 1-12.
Wong, K. Y., Tan, C. H., & Tan, N. H. (2016). Venom and purified toxins of the spectacled cobra (Naja naja) from Pakistan: Insights into toxicity and antivenom neutralization. The American journal of tropical medicine and hygiene, 94(6), 1392-1399.
Tan, C. H.; Liew, J. L.; Tan, K. Y.; Tan, N. H. (2016). Assessing SABU (Serum Anti Bisa Ular), the sole Indonesian antivenom: A proteomic analysis and neutralization efficacy study. Sci Rep. 6: 37299.
Tan, C. H.; Liew, J. L.; Tan, K. Y.; Tan, N. H. (2016). Genus Calliophis of Asiatic coral snakes: A deficiency of venom cross-reactivity and neutralization against seven regional elapid antivenoms. Toxicon 121:130-133.

2015

Yap, M. K. K., Tan, N. H., Sim, S. M., Fung, S. Y., & Tan, C. H. (2015). The Effect of a Polyvalent Antivenom on the Serum Venom Antigen Levels of Naja sputatrix (Javan Spitting Cobra) Venom in Experimentally Envenomed Rabbits. Basic & clinical pharmacology & toxicology, 117(4), 274-279.
Tan, K. Y., Tan, C. H., Fung, S. Y., & Tan, N. H. (2015). Venomics, lethality and neutralization of Naja kaouthia (monocled cobra) venoms from three different geographical regions of Southeast Asia. Journal of proteomics, 120, 105-125.
Sapsutthipas, S., Leong, P. K., Akesowan, S., Pratanaphon, R., Tan, N. H., & Ratanabanangkoon, K. (2015). Effective equine immunization protocol for production of potent poly-specific antisera against Calloselasma rhodostoma, Cryptelytrops albolabris and Daboia siamensis. PLoS Negl Trop Dis, 9(3), e0003609.
Leong, P. K., Fung, S. Y., Tan, C. H., Sim, S. M., & Tan, N. H. (2015). Immunological cross-reactivity and neutralization of the principal toxins of Naja sumatrana and related cobra venoms by a Thai polyvalent antivenom (Neuro Polyvalent Snake Antivenom). Acta tropica, 149, 86-93.
Tan, C. H., Tan, N. H., Tan, K. Y., & Kwong, K. O. (2015). Antivenom cross-neutralization of the venoms of Hydrophis schistosus and Hydrophis curtus, two common sea snakes in Malaysian waters. Toxins, 7(2), 572-581.
Tan, C. H., Tan, N. H., Sim, S. M., Fung, S. Y., & Gnanathasan, C. A. (2015). Proteomic investigation of Sri Lankan hump-nosed pit viper (Hypnale hypnale) venom. Toxicon, 93, 164-170.
Fung, S. Y., Lee, M. L., & Tan, N. H. (2015). Molecular mechanism of cell death induced by king cobra (Ophiophagus hannah) venom L-amino acid oxidase. Toxicon, 96, 38-45.
Tan, C. H., Tan, K. Y., Fung, S. Y., & Tan, N. H. (2015). Venom-gland transcriptome and venom proteome of the Malaysian king cobra (Ophiophagus hannah). BMC genomics, 16(1), 687.
Tan, N. H., Fung, S. Y., Tan, K. Y., Yap, M. K. K., Gnanathasan, C. A., & Tan, C. H. (2015). Functional venomics of the Sri Lankan Russell's viper (Daboia russelii) and its toxinological correlations. Journal of proteomics, 128, 403-423.

2014

Yap, M. K. K., Tan, N. H., Sim, S. M., Fung, S. Y., & Tan, C. H. (2014). Pharmacokinetics of Naja sumatrana (equatorial spitting cobra) venom and its major toxins in experimentally envenomed rabbits. PLoS Negl Trop Dis, 8(6), e2890.
Lee, M. L., Fung, S. Y., Chung, I., Pailoor, J., Cheah, S. H., & Tan, N. H. (2014). King cobra (Ophiophagus hannah) venom L-amino acid oxidase induces apoptosis in PC-3 cells and suppresses PC-3 solid tumor growth in a tumor xenograft mouse model. Int J Med Sci, 11(6), 593-601.
Yap, M. K. K., Fung, S. Y., Tan, K. Y., & Tan, N. H. (2014). Proteomic characterization of venom of the medically important Southeast Asian Naja sumatrana (Equatorial spitting cobra). Acta tropica, 133, 15-25.
Leong, P. K., Tan, C. H., Sim, S. M., Fung, S. Y., Sumana, K., Sitprija, V., & Tan, N. H. (2014). Cross neutralization of common Southeast Asian viperid venoms by a Thai polyvalent snake antivenom (Hemato Polyvalent Snake Antivenom). Acta tropica, 132, 7-14.
Tan, C. H., Sim, S. M., Gnanathasan, C. A., Fung, S. Y., & Tan, N. H. (2014). Pharmacokinetics of the Sri Lankan hump-nosed pit viper (Hypnale hypnale) venom following intravenous and intramuscular injections of the venom into rabbits. Toxicon, 79, 37-44.
Li Lee, M., Chung, I., Yee Fung, S., Kanthimathi, M. S., & Hong Tan, N. (2014). Antiproliferative Activity of King Cobra (Ophiophagus hannah) Venom l‐Amino Acid Oxidase. Basic & clinical pharmacology & toxicology, 114(4), 336-343.

2013

Sim, S. M., Saremi, K., Tan, N. H., & Fung, S. Y. (2013). Pharmacokinetics of Cryptelytrops purpureomaculates (mangrove pit viper) venom following intravenous and intramuscular injections in rabbits. International immunopharmacology, 17(4), 997-1001.
Fung, S. Y., & Tan, N. H. (2013). Isolation, characterization and antigenic cross-reactivities of the major hemorrhagin from Cryptelytrops purpureomaculatus venom. Ind J Exp Biol, 51, 1063-1069.
Yap, M. K. K., Tan, N. H., Sim, S. M., & Fung, S. Y. (2013). Toxicokinetics of Naja sputatrix (Javan spitting cobra) venom following intramuscular and intravenous administrations of the venom into rabbits. Toxicon, 68, 18-23.

2012

Tan, N. H., Fung, S. Y., & Yap, Y. H. Y. (2012). Isolation and characterization of the thrombin-like enzyme from Cryptelytrops albolabris (white-lipped tree viper) venom. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 161(1), 79-85.
Leong, P. K., Tan, N. H., Fung, S. Y., & Sim, S. M. (2012). Cross neutralisation of Southeast Asian cobra and krait venoms by Indian polyvalent antivenoms. Transactions of the Royal Society of Tropical Medicine and Hygiene, 106(12), 731-737.
Tan, C. H., Tan, N. H., Sim, S. M., Fung, S. Y., Jayalakshmi, P., & Gnanathasan, C. A. (2012). Nephrotoxicity of hump-nosed pit viper (Hypnale hypnale) venom in mice is preventable by the paraspecific Hemato polyvalent antivenom (HPA). Toxicon, 60(7), 1259-1262.
Leong, P. K., Sim, S. M., Fung, S. Y., Sumana, K., Sitprija, V., & Tan, N. H. (2012). Cross neutralization of Afro-Asian cobra and Asian krait venoms by a Thai polyvalent snake antivenom (Neuro Polyvalent Snake Antivenom). PLoS Negl Trop Dis, 6(6), e1672.
Tan, C. H., Tan, N. H., Sim, S. M., Fung, S. Y., & Gnanathasan, C. A. (2012). Immunological properties of Hypnale hypnale (hump-nosed pit viper) venom: antibody production with diagnostic and therapeutic potentials. Acta tropica, 122(3), 267-275.

2011

Yap, M. K. K., Tan, N. H., & Fung, S. Y. (2011). Biochemical and toxinological characterization of Naja sumatrana (Equatorial spitting cobra) venom. Journal of Venomous Animals and Toxins Including Tropical Diseases, 17(4), 451-459.
Tan, C. H., Sim, S. M., Gnanathasan, C. A., Fung, S. Y., Ponnudurai, G., Pailoor, J., & Tan, N. H. (2011). Enzymatic and toxinological activities of Hypnale hypnale (hump-nosed pit viper) venom and its fractionation by ion exchange high performance liquid chromatography. Journal of Venomous Animals and Toxins including Tropical Diseases, 17(4), 473-485.
Tan, C. H., Leong, P. K., Fung, S. Y., Sim, S. M., Ponnudurai, G., Ariaratnam, C., Khomvilai, S., Sitprija, V. and Tan, N.H. (2011). Cross neutralization of Hypnale hypnale (hump-nosed pit viper) venom by polyvalent and monovalent Malayan pit viper antivenoms in vitro and in a rodent model. Acta tropica, 117(2), 119-124.
Lee, M. L., Tan, N. H., Fung, S. Y., & Sekaran, S. D. (2011). Antibacterial action of a heat-stable form of L-amino acid oxidase isolated from king cobra (Ophiophagus hannah) venom. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 153(2), 237-242.

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